In SAS Process, the material is dissolved in a solvent and then sprayed into a high pressure chamber filled with Supercritical CO2. As each droplet is found in the high pressure vessel the CO2 extracts the solvent leaving behind the powder. By changing the pressure, temperature leaves dry particles in the vessel.
Rapid Expansion of Supercritical Solutions (RESS)
SuperParticle RESS Systems are versatile, skid-mounted, PC-controlled systems capable of producing micron-size powders of thermally labile materials. The RESS process incorporates carbon dioxide as a solvent, which reduces processing costs, is non-toxic, and leaves no residue.
Non–polar materials can be dissolved in supercritical carbon dioxide and sprayed, as in spray drying. This technique is called RESS. RESS Systems allow researchers to mix carbon dioxide with their samples in a high-pressure, agitated vessel. This allows non-polar compounds to be sprayed through a nozzle from a supercritical solution. By manipulating the pressure, temperature and concentration, the user can manipulate powder sizes.This non-polar misture is then sprayed through a heated sapphire nozzle assembly.
RESS Systems are appropriate for pharmaceutical applications, including:
SuperReactor and Reactor Systems are designed and fabricated for researchers who are interested in investigating chemical reactions, or performing process studies under elevated temperatures and pressures.
Features of this compact system can include sapphire windows for direct or video camera viewing, magnetically coupled stirring, and process ports located in the body and cover assembly. Using Waters’ process controller, researchers can control heating, display pressure, temperature, alarms, and data log process conditions to their PCs. Users can also choose a reactor configuration ranging from a base reactor, to one with windows, to a complete package with a process controller and liquid pumps.
Options can also be added, as the users’ needs change, providing maximum flexibility.